Developing Covid-19 Vaccines at Pandemic Speed | Safety, tolerability, and immunogenicity of a recombinant adenovirus type-5 vectored COVID-19 vaccine: a dose-escalation, open-label, non-randomised, first-in-human trial | Hydroxychloroquine or chloroquine with or without a macrolide for treatment of COVID-19: a multinational registry analysis
An outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic: an observational cohort study | Preventing a Parallel Pandemic — A National Strategy to Protect Clinicians’ Well-Being | Triple combination of interferon beta-1b, lopinavir–ritonavir, and ribavirin in the treatment of patients admitted to hospital with COVID-19: an open-label, randomised, phase 2 trial
Arterial thromboembolic complications in COVID-19 in low risk patients despite prophylaxis | Association of Treatment With Hydroxychloroquine or Azithromycin With In-Hospital Mortality in Patients With COVID-19 in New York State | Observational Study of Hydroxychloroquine in Hospitalized Patients with Covid-19
By Dickson Despommier —
Since their establishment some 11,000 years ago, as of 2020, cities with populations greater than one hundred thousand have evolved and grown to accommodate some 60% of us (that’s 4.4 billion individuals). The trend is clear. In another 50 years it is estimated that over 80% of the human population will live in cities.
The Recovery Trial is a multi-arm multi-stage adaptive trial with mortality as the primary endpoint together with a 10 year follow up period linked to the electronic health records of ~6900 Covid-19 patients in the UK enrolled to date treated with either: placebo or ritonavir/lopinavir or steroids or azithromycin or hydroxy-chloroquine.