Weekly Clinical Updates

As infectious diseases such as SARS, Monkeypox, Polio, HIV, and Ebola travel the globe and garner media attention, Parasites Without Borders staff are curating resources in a timely, ongoing basis. We believe the information posted here is worthy of further examination by the science and medical communities. Our primary goal remains to bring the latest medical and biological information to the forefront for researchers and practicing physicians.

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January 19, 2023

Long COVID: major findings, mechanisms and recommendations | Effect of using a structured pacing protocol on post-exertional symptom exacerbation and health status in a longitudinal cohort with the post-COVID-19 syndrome | Detection of SARS-CoV-2 IgA and IgG in human milk and breastfeeding infant stool 6 months after maternal COVID-19 vaccination | Effect of Fluvoxamine vs Placebo on Time to Sustained Recovery in Outpatients With Mild to Moderate COVID-19 | Hyperimmune Globulin for Severely Immunocompromised Patients Hospitalized With Coronavirus Disease 2019

January 12, 2023

Long covid outcomes at one year after mild SARS-CoV-2 infection: nationwide cohort study | Effectiveness of the Bivalent mRNA Vaccine in Preventing Severe COVID-19 Outcomes: An Observational Cohort Study | 7-month duration of SARS-CoV-2 mucosal immunoglobulin-A responses and protection | Increasing Ventilation Reduces Sars-Cov-2 Airborne Transmission In Schools | Use of Carbon Dioxide Monitoring to Assess Ventilation at a National Infectious Diseases Conference

January 5, 2023

Virological characteristics of the SARS-CoV-2 XBB variant | SARS-CoV-2 infection and persistence in the human body | Long-term cardiovascular outcomes of COVID-19 | Heart-disease risk soars | Alarming antibody evasion properties of rising SARS-CoV-2 BQ and XBB subvariants | Comparative effectiveness of third doses of mRNA-based COVID-19 vaccines | Time to negative PCR conversion among high-risk patients | The Fc-effector function of COVID-19 convalescent plasma | Infectiousness of SARS-CoV-2 breakthrough infections and reinfections

December 29, 2022

Antibody-dependent cellular cytotoxicity against SARS-CoV-2 Omicron | Structural brain changes in post-acute COVID-19 patients | Persistent post–COVID-19 smell loss | Persistent symptoms and sequelae after SARS-CoV-2 infection | VV116 versus Nirmatrelvir–Ritonavir for Oral Treatment of Covid-19 | Nirmatrelvir Plus Ritonavir for Early COVID-19 in a Large U.S. Health System | Molnupiravir plus usual care versus usual care alone as early treatment for adults | Higher dose corticosteroids in hospitalized COVID-19 patients | FDA approves Roche’s Actemra (tocilizumab) for the treatment of COVID-19 | Outpatient treatment of Covid-19 with metformin, ivermectin, and fluvoxamine | Canine real-time detection of SARS-CoV-2 infections | Clinical Validation of a Novel T-Cell Receptor | Modelling the adjustment of COVID-19 response | Two masks can be worse than one: N95 respirator failure caused by an overlying face mask | Airflow Patterns in Double-Occupancy Patient Rooms | The epidemiology of long COVID in US adults

December 22, 2022

Immunological dysfunction persists for 8 months | Clinical Features and Burden of Post-Acute Sequelae of SARS-CoV-2 Infection | Demonstration of stable clusters of symptoms | Longitudinal Analysis of T cells in COVID-19 | Reconsideration of anti-nucleocapsid IgG antibody | Early Estimates of Bivalent mRNA Vaccine | Early Estimates of Bivalent mRNA Vaccine Effectiveness in Preventing COVID-19–Associated Hospitalization | Effect of Nirmatrelvir/Ritonavir versus Placebo on COVID-19─Related Hospitalizations | COVID-19 Convalescent Plasma Outpatient Therapy | Bacterial Co-infection and Empirical Antibiotic Therapy in Patients | Similar SARS-CoV-2 Ct value distributions in anterior nares versus nasopharyngeal samples | Prevalence of SARS-CoV-2 and Influenza Coinfection and Clinical Characteristics | The WHO estimates of excess mortality associated with the COVID-19 pandemic | Impact of SARS-CoV-2 variants on inpatient clinical outcome | Association of Time to Surgery After COVID-19 Infection
Epidemiology Researcher

December 15, 2022

Progress Toward Poliomyelitis Eradication ― Afghanistan | Moderna Received FDA Emergency Use Authorization For Their Omicron-Targeting Bivalent Covid-19 Booster Vaccine In Children | Reduced Risk for Mpox After Receipt of 1 or 2 Doses of JYNNEOS Vaccine Compared with Risk Among Unvaccinated Persons | Authorized Updated (Bivalent) COVID-19 Vaccines for Children | Low neutralization of SARS-CoV-2 Omicron BA.2.75.2, BQ.1.1, and XBB.1 by parental mRNA vaccine or a BA.5-bivalent booster | Incidence of Viral Rebound After Treatment With Nirmatrelvir-Ritonavir and Molnupiravir | The effectiveness of coronavirus disease 2019 (COVID-19) vaccine in the prevention of post–COVID-19 conditions | Reduced airborne transmission of SARS-CoV-2 BA.1 Omicron virus in Syrian hamsters

Situation Dashboards

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World Health Organization (WHO)

Novel Coronavirus (COVID-19) Situation from World Health Organization (WHO)
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Johns Hopkins University (JHU)

Coronavirus COVID-19 Global Cases by the Center for Systems Science and Engineering (CSSE) at JHU
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COVID-19 in US and Canada

1Point3Acres Real-Time Coronavirus (COVID-19) Updates in US and Canada with Credible Sources
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Genomic Epidemiology COVID-19

Genomic Epidemiology of (COVID-19) Maintained by the Nextstrain team, enabled by data from GISAID.

Sources for COVID-19 Information

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World Health Organization (WHO)

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Centers for Disease Control, US

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International Society for Infectious Diseases

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This Week in Virology (TWIV)

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