{"id":10203,"date":"2020-06-05T03:40:02","date_gmt":"2020-06-05T03:40:02","guid":{"rendered":"https:\/\/parasiteswithoutborders.com\/?p=10203"},"modified":"2022-08-26T21:16:40","modified_gmt":"2022-08-26T21:16:40","slug":"june-4-2020","status":"publish","type":"post","link":"https:\/\/parasiteswithoutborders.com\/es\/june-4-2020\/","title":{"rendered":"June 4, 2020"},"content":{"rendered":"<ul>\n<li><a href=\"https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa2016638?query=featured_home\" target=\"_blank\" rel=\"noopener\"><strong>A Randomized Trial of Hydroxychloroquine as Postexposure Prophylaxis for Covid-19<\/strong><\/a><br \/>\n<em>Authors conducted a randomized, double-blind, placebo-controlled trial across the United States and parts of Canada testing hydroxychloroquine as postexposure prophylaxis. Authors enrolled adults who had household or occupational exposure to someone with confirmed Covid-19 at a distance of less than 6 ft for more than 10 minutes while wearing neither a face mask nor an eye shield (high-risk exposure) or while wearing a face mask but no eye shield (moderate-risk exposure). Within 4 days after exposure, participants were randomly assigned to receive either placebo or hydroxychloroquine (800 mg once, followed by 600 mg in 6 to 8 hours, then 600 mg daily for 4 additional days). The primary outcome was the incidence of either laboratory-confirmed Covid-19 or illness compatible with Covid-19 within 14 days. After high-risk or moderate-risk exposure to Covid-19, hydroxychloroquine did not prevent illness compatible with Covid-19 or confirmed infection when used as postexposure prophylaxis within 4 days after exposure. <\/em><\/li>\n<\/ul>\n\t<ul>\n<li><a href=\"https:\/\/academic.oup.com\/cid\/advance-article\/doi\/10.1093\/cid\/ciaa638\/5842165\" target=\"_blank\" rel=\"noopener\"><strong>Predicting infectious SARS-CoV-2 from diagnostic samples<\/strong><\/a><br \/>\n<em>RT-PCR has become the primary method to diagnose viral diseases, including SARS-CoV-2. RT-PCR detects RNA, not infectious virus, thus its ability to determine duration of infectivity of patients is limited. Infectivity is a critical determinant in informing public health guidelines\/interventions. Authors goal was to determine the relationship between E gene SARS-CoV-2 RT-PCR cycle threshold (Ct) values from respiratory samples, symptom onset to test (STT) and infectivity in cell culture. SARS-CoV-2 Vero cell infectivity was only observed for RT-PCR Ct < 24 and STT < 8 days. Infectivity of patients with Ct >24 and duration of symptoms >8 days may be low.<\/em><\/li>\n<\/ul>\n\t<ul>\n<li><a href=\"https:\/\/www.thelancet.com\/action\/showPdf?pii=S0140-6736%2820%2931142-9\" target=\"_blank\" rel=\"noopener\"><strong>Physical distancing, face masks, and eye protection to prevent person-to-person transmission of SARS-CoV-2 and COVID-19: a systematic review and meta-analysis<\/strong><\/a><br \/>\n<em>Authors conducted a systematic review and meta-analysis to investigate the optimum distance for avoiding person-to- person virus transmission and to assess the use of face masks and eye protection to prevent transmission of viruses. Data for SARS-CoV-2 and the betacoronaviruses that cause severe acute respiratory syndrome, and Middle East respiratory syndrome were obtained from 21 standard WHO-specific and COVID-19-specific sources. The findings of this systematic review and meta-analysis support physical distancing of 1 m or more and provide quantitative estimates for models and contact tracing to inform policy.<\/em><\/li>\n<\/ul>\n\t<h3>\n\t\t\t\tSituation Dashboards\n\t\t\t<\/h3>\n\t\t\t\t<img decoding=\"async\" data-src=\"https:\/\/b1663976.smushcdn.com\/1663976\/wp-content\/uploads\/2020\/03\/World_Health_Organization_logo_logotype-300x89.png?lossy=1&strip=1&webp=1\" alt=\"World_Health_Organization_logo_logotype\" title=\"World_Health_Organization_logo_logotype\" itemprop=\"image\" data-srcset=\"https:\/\/b1663976.smushcdn.com\/1663976\/wp-content\/uploads\/2020\/03\/World_Health_Organization_logo_logotype-300x89.png?lossy=1&amp;strip=1&amp;webp=1 300w, https:\/\/b1663976.smushcdn.com\/1663976\/wp-content\/uploads\/2020\/03\/World_Health_Organization_logo_logotype-1024x302.png?lossy=1&amp;strip=1&amp;webp=1 1024w, https:\/\/b1663976.smushcdn.com\/1663976\/wp-content\/uploads\/2020\/03\/World_Health_Organization_logo_logotype-768x227.png?lossy=1&amp;strip=1&amp;webp=1 768w, https:\/\/b1663976.smushcdn.com\/1663976\/wp-content\/uploads\/2020\/03\/World_Health_Organization_logo_logotype-1536x453.png?lossy=1&amp;strip=1&amp;webp=1 1536w, https:\/\/b1663976.smushcdn.com\/1663976\/wp-content\/uploads\/2020\/03\/World_Health_Organization_logo_logotype-2048x604.png?lossy=1&amp;strip=1&amp;webp=1 2048w\" data-sizes=\"auto\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" class=\"lazyload\" style=\"--smush-placeholder-width: 300px; --smush-placeholder-aspect-ratio: 300\/89;\" data-original-sizes=\"(max-width: 300px) 100vw, 300px\" \/>\n\t\t<h3>World Health Organization (WHO)<\/h3>\t\t\t\nNovel Coronavirus (COVID-19) Situation from World Health Organization (WHO)\n\t\t\t<a href=\"https:\/\/experience.arcgis.com\/experience\/685d0ace521648f8a5beeeee1b9125cd\" target=\"_blank\" rel=\"noopener\" role=\"button\" aria-label=\"View Dashboard\">\n\t\t\t\t\t\t\tView Dashboard\n\t\t<\/a>\n\t\t\t\t<img decoding=\"async\" data-src=\"https:\/\/b1663976.smushcdn.com\/1663976\/wp-content\/uploads\/2020\/03\/university-logo-small-horizontal-blue-no-clear-space-51c7fb4524-300x57.png?lossy=1&strip=1&webp=1\" alt=\"university-logo-small-horizontal-blue-no-clear-space-51c7fb4524\" title=\"university-logo-small-horizontal-blue-no-clear-space-51c7fb4524\" itemprop=\"image\" data-srcset=\"https:\/\/b1663976.smushcdn.com\/1663976\/wp-content\/uploads\/2020\/03\/university-logo-small-horizontal-blue-no-clear-space-51c7fb4524-300x57.png?lossy=1&amp;strip=1&amp;webp=1 300w, https:\/\/b1663976.smushcdn.com\/1663976\/wp-content\/uploads\/2020\/03\/university-logo-small-horizontal-blue-no-clear-space-51c7fb4524-768x145.png?lossy=1&amp;strip=1&amp;webp=1 768w, https:\/\/b1663976.smushcdn.com\/1663976\/wp-content\/uploads\/2020\/03\/university-logo-small-horizontal-blue-no-clear-space-51c7fb4524.png?lossy=1&amp;strip=1&amp;webp=1 908w\" data-sizes=\"auto\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" class=\"lazyload\" style=\"--smush-placeholder-width: 300px; --smush-placeholder-aspect-ratio: 300\/57;\" data-original-sizes=\"(max-width: 300px) 100vw, 300px\" \/>\n\t\t<h3>Johns Hopkins University (JHU)<\/h3>\t\t\t\nCoronavirus COVID-19 Global Cases by the Center for Systems Science and Engineering (CSSE) at JHU\n\t\t\t<a href=\"https:\/\/gisanddata.maps.arcgis.com\/apps\/opsdashboard\/index.html#\/bda7594740fd40299423467b48e9ecf6\" target=\"_blank\" rel=\"noopener\" role=\"button\" aria-label=\"View Dashboard\">\n\t\t\t\t\t\t\tView Dashboard\n\t\t<\/a>\n\t\t\t\t<img decoding=\"async\" data-src=\"https:\/\/b1663976.smushcdn.com\/1663976\/wp-content\/uploads\/2020\/03\/1point3acres-300x83.png?lossy=1&strip=1&webp=1\" alt=\"1point3acres\" title=\"1point3acres\" itemprop=\"image\" data-srcset=\"https:\/\/b1663976.smushcdn.com\/1663976\/wp-content\/uploads\/2020\/03\/1point3acres-300x83.png?lossy=1&amp;strip=1&amp;webp=1 300w, https:\/\/b1663976.smushcdn.com\/1663976\/wp-content\/uploads\/2020\/03\/1point3acres-1024x283.png?lossy=1&amp;strip=1&amp;webp=1 1024w, https:\/\/b1663976.smushcdn.com\/1663976\/wp-content\/uploads\/2020\/03\/1point3acres-768x212.png?lossy=1&amp;strip=1&amp;webp=1 768w, https:\/\/b1663976.smushcdn.com\/1663976\/wp-content\/uploads\/2020\/03\/1point3acres-1536x425.png?lossy=1&amp;strip=1&amp;webp=1 1536w, https:\/\/b1663976.smushcdn.com\/1663976\/wp-content\/uploads\/2020\/03\/1point3acres.png?lossy=1&amp;strip=1&amp;webp=1 1837w\" data-sizes=\"auto\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" class=\"lazyload\" style=\"--smush-placeholder-width: 300px; --smush-placeholder-aspect-ratio: 300\/83;\" data-original-sizes=\"(max-width: 300px) 100vw, 300px\" \/>\n\t\t<h3>COVID-19 in US and Canada<\/h3>\t\t\t\n1Point3Acres Real-Time Coronavirus (COVID-19) Updates in US and Canada with Credible Sources\n\t\t\t<a href=\"https:\/\/coronavirus.1point3acres.com\/\" target=\"_blank\" rel=\"noopener\" role=\"button\" aria-label=\"View Dashboard\">\n\t\t\t\t\t\t\tView Dashboard\n\t\t<\/a>\n\t\t\t\t<img decoding=\"async\" data-src=\"https:\/\/b1663976.smushcdn.com\/1663976\/wp-content\/uploads\/2020\/03\/image-300x76.png?lossy=1&strip=1&webp=1\" alt=\"image\" title=\"image\" itemprop=\"image\" data-srcset=\"https:\/\/b1663976.smushcdn.com\/1663976\/wp-content\/uploads\/2020\/03\/image-300x76.png?lossy=1&amp;strip=1&amp;webp=1 300w, https:\/\/b1663976.smushcdn.com\/1663976\/wp-content\/uploads\/2020\/03\/image-768x195.png?lossy=1&amp;strip=1&amp;webp=1 768w, https:\/\/b1663976.smushcdn.com\/1663976\/wp-content\/uploads\/2020\/03\/image.png?lossy=1&amp;strip=1&amp;webp=1 866w\" data-sizes=\"auto\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" class=\"lazyload\" style=\"--smush-placeholder-width: 300px; --smush-placeholder-aspect-ratio: 300\/76;\" data-original-sizes=\"(max-width: 300px) 100vw, 300px\" \/>\n\t\t<h3>Genomic Epidemiology COVID-19<\/h3>\t\t\t\nGenomic Epidemiology of (COVID-19) Maintained by the Nextstrain team, enabled by data from GISAID.\n\t\t\t<a href=\"https:\/\/nextstrain.org\/ncov\" target=\"_blank\" rel=\"noopener\" role=\"button\" aria-label=\"View Dashboard\">\n\t\t\t\t\t\t\tView Dashboard\n\t\t<\/a>\n\t<h3>\n\t\t\t\tSources for COVID-19 Information\n\t\t\t<\/h3>\n\t<a href=\"https:\/\/www.who.int\/\" target=\"_blank\" rel=\"noopener\"><\/a> \n\t\t\t\t<img decoding=\"async\" data-src=\"https:\/\/b1663976.smushcdn.com\/1663976\/wp-content\/uploads\/2020\/03\/World_Health_Organization_logo_logotype-300x89.png?lossy=1&strip=1&webp=1\" alt=\"World_Health_Organization_logo_logotype\" title=\"World_Health_Organization_logo_logotype\" itemprop=\"image\" data-srcset=\"https:\/\/b1663976.smushcdn.com\/1663976\/wp-content\/uploads\/2020\/03\/World_Health_Organization_logo_logotype-300x89.png?lossy=1&amp;strip=1&amp;webp=1 300w, https:\/\/b1663976.smushcdn.com\/1663976\/wp-content\/uploads\/2020\/03\/World_Health_Organization_logo_logotype-1024x302.png?lossy=1&amp;strip=1&amp;webp=1 1024w, https:\/\/b1663976.smushcdn.com\/1663976\/wp-content\/uploads\/2020\/03\/World_Health_Organization_logo_logotype-768x227.png?lossy=1&amp;strip=1&amp;webp=1 768w, https:\/\/b1663976.smushcdn.com\/1663976\/wp-content\/uploads\/2020\/03\/World_Health_Organization_logo_logotype-1536x453.png?lossy=1&amp;strip=1&amp;webp=1 1536w, https:\/\/b1663976.smushcdn.com\/1663976\/wp-content\/uploads\/2020\/03\/World_Health_Organization_logo_logotype-2048x604.png?lossy=1&amp;strip=1&amp;webp=1 2048w\" data-sizes=\"auto\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" class=\"lazyload\" style=\"--smush-placeholder-width: 300px; --smush-placeholder-aspect-ratio: 300\/89;\" data-original-sizes=\"(max-width: 300px) 100vw, 300px\" \/>\n\t\t<h3>World Health Organization (WHO)<\/h3>\t\t\t\n\t<a href=\"https:\/\/www.cdc.gov\/\" target=\"_blank\" rel=\"noopener\"><\/a> \n\t\t\t\t<img decoding=\"async\" data-src=\"https:\/\/b1663976.smushcdn.com\/1663976\/wp-content\/uploads\/2020\/03\/1280px-US_CDC_logo.svg-300x227.png?lossy=1&strip=1&webp=1\" alt=\"1280px-US_CDC_logo.svg\" title=\"1280px-US_CDC_logo.svg\" itemprop=\"image\" data-srcset=\"https:\/\/b1663976.smushcdn.com\/1663976\/wp-content\/uploads\/2020\/03\/1280px-US_CDC_logo.svg-300x227.png?lossy=1&amp;strip=1&amp;webp=1 300w, https:\/\/b1663976.smushcdn.com\/1663976\/wp-content\/uploads\/2020\/03\/1280px-US_CDC_logo.svg-1024x774.png?lossy=1&amp;strip=1&amp;webp=1 1024w, https:\/\/b1663976.smushcdn.com\/1663976\/wp-content\/uploads\/2020\/03\/1280px-US_CDC_logo.svg-768x580.png?lossy=1&amp;strip=1&amp;webp=1 768w, https:\/\/b1663976.smushcdn.com\/1663976\/wp-content\/uploads\/2020\/03\/1280px-US_CDC_logo.svg.png?lossy=1&amp;strip=1&amp;webp=1 1280w\" data-sizes=\"auto\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" class=\"lazyload\" style=\"--smush-placeholder-width: 300px; --smush-placeholder-aspect-ratio: 300\/227;\" data-original-sizes=\"(max-width: 300px) 100vw, 300px\" \/>\n\t\t<h3>Centers for Disease Control, US<\/h3>\t\t\t\n\t<a href=\"https:\/\/promedmail.org\/\" target=\"_blank\" rel=\"noopener\"><\/a> \n\t\t\t\t<img decoding=\"async\" data-src=\"https:\/\/b1663976.smushcdn.com\/1663976\/wp-content\/uploads\/2020\/03\/ProMED-Logo-300x72.png?lossy=1&strip=1&webp=1\" alt=\"ProMED-Logo\" title=\"ProMED-Logo\" itemprop=\"image\" data-srcset=\"https:\/\/b1663976.smushcdn.com\/1663976\/wp-content\/uploads\/2020\/03\/ProMED-Logo-300x72.png?lossy=1&amp;strip=1&amp;webp=1 300w, https:\/\/b1663976.smushcdn.com\/1663976\/wp-content\/uploads\/2020\/03\/ProMED-Logo.png?lossy=1&amp;strip=1&amp;webp=1 444w\" data-sizes=\"auto\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" class=\"lazyload\" style=\"--smush-placeholder-width: 300px; --smush-placeholder-aspect-ratio: 300\/72;\" data-original-sizes=\"(max-width: 300px) 100vw, 300px\" \/>\n\t\t<h3>International Society for Infectious Diseases<\/h3>\t\t\t\n\t<a href=\"http:\/\/www.microbe.tv\/twiv\/\" target=\"_blank\" rel=\"noopener\"><\/a> \n\t\t\t\t<img decoding=\"async\" data-src=\"https:\/\/b1663976.smushcdn.com\/1663976\/wp-content\/uploads\/2020\/03\/twiv-logo.png?lossy=1&strip=1&webp=1\" alt=\"twiv-logo\" title=\"twiv-logo\" itemprop=\"image\" data-sizes=\"(max-width: 265px) 100vw, 265px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" class=\"lazyload\" style=\"--smush-placeholder-width: 265px; --smush-placeholder-aspect-ratio: 265\/86;\" \/>\n\t\t<h3>This Week in Virology (TWIV)<\/h3>","protected":false},"excerpt":{"rendered":"<p>A Randomized Trial of Hydroxychloroquine as Postexposure Prophylaxis for Covid-19 |   Predicting infectious SARS-CoV-2 from diagnostic samples | Physical distancing, face masks, and eye protection to prevent person-to-person transmission of SARS-CoV-2 and COVID-19: a systematic review and meta-analysis<\/p>","protected":false},"author":1,"featured_media":10243,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"wds_primary_category":0,"footnotes":""},"categories":[85,81],"tags":[],"post_folder":[],"class_list":["post-10203","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-clinical-updates","category-covid19"],"_links":{"self":[{"href":"https:\/\/parasiteswithoutborders.com\/es\/wp-json\/wp\/v2\/posts\/10203","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/parasiteswithoutborders.com\/es\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/parasiteswithoutborders.com\/es\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/parasiteswithoutborders.com\/es\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/parasiteswithoutborders.com\/es\/wp-json\/wp\/v2\/comments?post=10203"}],"version-history":[{"count":0,"href":"https:\/\/parasiteswithoutborders.com\/es\/wp-json\/wp\/v2\/posts\/10203\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/parasiteswithoutborders.com\/es\/wp-json\/wp\/v2\/media\/10243"}],"wp:attachment":[{"href":"https:\/\/parasiteswithoutborders.com\/es\/wp-json\/wp\/v2\/media?parent=10203"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/parasiteswithoutborders.com\/es\/wp-json\/wp\/v2\/categories?post=10203"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/parasiteswithoutborders.com\/es\/wp-json\/wp\/v2\/tags?post=10203"},{"taxonomy":"post_folder","embeddable":true,"href":"https:\/\/parasiteswithoutborders.com\/es\/wp-json\/wp\/v2\/post_folder?post=10203"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}