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- COVID-19 Lung Injury is Not High Altitude Pulmonary Edema
Authors correct the misconception that COVID- 19 lung injury is not like typical acute respiratory distress syndrome (ARDS) and instead is similar to high altitude pulmonary edema (HAPE). They argue that treatments for HAPE may exacerbate ARDS. - Association of Inpatient Use of Angiotensin Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers with Mortality Among Patients With Hypertension Hospitalized With COVID-19
Among hospitalized COVID-19 patients with hypertension, inpatient use of ACEI/ARB was associated with lower risk of all-cause mortality compared with ACEI/ARB non-users. While study interpretation needs to consider the potential for residual confounders, it is unlikely that in-hospital use of ACEI/ARB was associated with an increased mortality risk. - Factors associated with hospitalization and critical illness among 4,103 patients with COVID-19 disease in New York City
A cross-sectional analysis of 4,103 patients with laboratory-confirmed COVID-19 at a single academic health system in New York City. Age and comorbidities are powerful predictors of hospitalization; however, admission oxygen impairment and markers of inflammation are most strongly associated with critical illness.
- Hydroxychloroquine in patients with COVID-19: an open-label, randomized, controlled trial
A 150 patient open-label randomized study comparing hydroxychloroquine to standard of care failed to demonstrate a difference in the primary endpoint of PCR viral clearance at day 28. Treatment was started a mean16.6 days after symptom onset. A secondary endpoint on “alleviating symptoms” was reported as significant however it was only in a minority of the total patients enrolled.
Situation Dashboards
World Health Organization (WHO)
Novel Coronavirus (COVID-19) Situation from World Health Organization (WHO)
Johns Hopkins University (JHU)
Coronavirus COVID-19 Global Cases by the Center for Systems Science and Engineering (CSSE) at JHU
COVID-19 in US and Canada
1Point3Acres Real-Time Coronavirus (COVID-19) Updates in US and Canada with Credible Sources
Genomic Epidemiology COVID-19
Genomic Epidemiology of (COVID-19) Maintained by the Nextstrain team, enabled by data from GISAID.
