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- Arterial thromboembolic complications in COVID-19 in low risk patients despite prophylaxis
Authors present a case series of three patients with COVID-19 who developed arterial vascular complications, one who developed an acute CVA, one who developed popliteal artery occlusion and one who developed both during their hospital course. - Association of Treatment With Hydroxychloroquine or Azithromycin With In-Hospital Mortality in Patients With COVID-19 in New York State
Among patients hospitalized in metropolitan New York with COVID-19, treatment with hydroxychloroquine, azithromycin, or both, compared with neither treatment, was not significantly associated with differences in in-hospital mortality. However, the interpretation of these findings may be limited by the observational design. - Observational Study of Hydroxychloroquine in Hospitalized Patients with Covid-19
In this observational study involving patients with Covid-19 who had been admitted to the hospital, hydroxychloroquine administration was not associated with either a greatly lowered or an increased risk of the composite end point of intubation or death. Randomized, controlled trials of hydroxychloroquine in patients with Covid-19 are needed.
- A strategic approach to COVID-19 vaccine R&D
Authors call for a public-private partnership and platform for harmonized clinical trials aims to accelerate licensure and distribution.
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