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Interim Estimated Effectiveness of 2025-2026 COVID-19 Vaccines in Adults Using a Test-Negative Design
These are the results of a case-control study of 85,725 emergency department and urgent care (ED/UC) encounters and 26,073 hospitalizations in immunocompetent adults aged 18 years or older with a COVID-19–like illness. Estimated effectiveness of 2025-2026 COVID-19 vaccination was 50% against COVID-19–associated ED/UC encounters and 55% against COVID-19–associated hospitalization, compared with not receiving a 2025-2026 vaccine dose.
CDC reports 294 influenza-associated pediatric deaths occurred during the 2024-2025 season
This is the highest number of pediatric deaths reported in any non-pandemic influenza season since the condition became reportable.
U.S. Military Requires Flu Vaccine for Some after Outbreak in Texas Training Center
The U.S. military has resumed requiring flu vaccines for some service members in an exception to Defense Secretary Pete Hegseth's guidance declaring the shots voluntary two months ago. The decision follows a flu outbreak among recruits at Joint Base San Antonio-Lackland in Texas and sharp criticism of the policy from public health experts. More than 220 recruits have been diagnosed with influenza and four hospitalized in the outbreak this month, according to media reports.
FDA Approves First Generic Version of Roche's Flu Drug
The U.S. Food and Drug Administration approved the first generic version of Roche's Xofluza (Baloxavir), a single-dose flu medicine for certain patients aged 5 years and older. Generic baloxavir marboxil tablets can be used to treat uncomplicated flu in patients who have had symptoms for no more than 48 hours, including those who are otherwise healthy or at high risk of flu-related complications. The drug can also be used to help prevent flu after contact with an infected person.
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COVID-19 in US and Canada
