Clinical Updates

12 Months of Trauma: More Than 3,600 US Health Workers Died in Covid’s First Year | Characteristics and Disease Severity of US Children and Adolescents Diagnosed With COVID-19 | Physical inactivity is associated with a higher risk for severe COVID-19 outcomes: a study in 48 440 adult patients

Characteristics and Outcomes of US Children and Adolescents With Multisystem Inflammatory Syndrome in Children (MIS-C) Compared With Severe Acute COVID-19 | Post-covid syndrome in individuals admitted to hospital with covid-19: retrospective cohort study

Provisional Death Counts for Coronavirus Disease 2019 (COVID-19) | Pfizer-BioNtech announce positive topline results of pivotal COVID-19 vaccine study in adolescents | FDA Authorizes Cue Health’s COVID-19 Test for At-Home and Over The Counter Use

Aspirin Use Is Associated With Decreased Mechanical Ventilation, Intensive Care Unit Admission, and In-Hospital Mortality in Hospitalized Patients With Coronavirus Disease 2019 | Post-acute COVID-19 syndrome | Are vaccines safe in patients with Long COVID? A prospective observational study

Lilly’s bamlanivimab and etesevimab together reduced hospitalizations and death in Phase 3 trial for early COVID-19 | Ridgeback Biotherapeutics and Merck Announce Preliminary Findings from a Phase 2a Trial of Investigational COVID-19 Therapeutic Molnupiravir

Difference in SARS-CoV-2 attack rate between children and adults may reflect bias | Update on long COVID prevalence estimate | Association of Convalescent Plasma Treatment With Clinical Outcomes in Patients With COVID-19 | Dexamethasone in Hospitalized Patients with Covid-19

Use of non-steroidal anti-inflammatory drugs and risk of death from COVID-19: an OpenSAFELY cohort analysis based on two cohorts | Inhaled budesonide in the treatment of early COVID-19 illness: a randomised controlled trial | Sequelae in Adults at 6 Months After COVID-19 Infection

Early initiation of prophylactic anticoagulation for prevention of coronavirus disease 2019 mortality in patients admitted to hospital in the United States: cohort study | Multisystem Inflammatory Syndrome in Children (MIS-C) | Decreased SARS-CoV-2 viral load following vaccination

Full-dose blood thinners decreased need for life support and improved outcome in hospitalized COVID-19 patients | Increased Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 to Antibody Neutralization | Single Dose Vaccination in Healthcare Workers Previously Infected with SARS-CoV-2

Novavax COVID-19 Vaccine Demonstrates 89.3% Efficacy in UK Phase 3 Trial | Johnson & Johnson Announces Single-Shot Janssen COVID-19 Vaccine Candidate Met Primary Endpoints in Interim Analysis of its Phase 3 ENSEMBLE Trial | SARS-CoV-2 Neutralizing Antibody LY-CoV555 in Outpatients with Covid-19