Weekly Clinical Updates

As infectious diseases such as SARS, Monkeypox, Polio, HIV, and Ebola travel the globe and garner media attention, Parasites Without Borders staff are curating resources in a timely, ongoing basis. We believe the information posted here is worthy of further examination by the science and medical communities. Our primary goal remains to bring the latest medical and biological information to the forefront for researchers and practicing physicians.

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June 08,2023

Development of a Definition of Postacute Sequelae of SARS-CoV-2 Infection | Neuroinflammation After COVID-19 With Persistent Depressive and Cognitive Symptoms | Long COVID Clinical Phenotypes Up to Six Months After Infection Identified by Latent Class Analysis of Self-Reported Symptoms | Effectiveness of COVID-19 Treatment With Nirmatrelvir–Ritonavir or Molnupiravir Among U.S. Veterans: Target Trial Emulation Studies With One-Month and Six-Month Outcomes | Estimates of SARS-CoV-2 Seroprevalence and Incidence of Primary SARS-CoV-2 Infections Among Blood Donors, by COVID-19 Vaccination Status | Smart Thermometer–Based Participatory Surveillance to Discern the Role of Children in Household Viral Transmission During the COVID-19 Pandemic | Changing Severity and Epidemiology of Adults Hospitalized With Coronavirus Disease 2019 (COVID-19) in the United States After Introduction of COVID-19 Vaccines, March 2021–August 2022 | National Trends in Anticoagulation Therapy for COVID-19 Hospitalized Adults in the United States: Analyses of the National COVID Cohort Collaborative | Coronary microvascular health in symptomatic patients with prior COVID-19 infection: an updated analysis

May 31,2023

Association between SARS-CoV-2 variants and frequency of acute symptoms: Analysis of a multi-institutional prospective cohort study - December 20, 2020 – June 20, 2022 | Development of a Definition of Postacute Sequelae of SARS-CoV-2 Infection | Pfizer’s PAXLOVID™ Receiving FDA Approval for Adult Patients at High Risk of Progression to Severe COVID-19 | Potential for Recurrent Mpox Outbreaks Among Gay, Bisexual, and Other Men Who Have Sex with Men — United States, 2023 | A Prospective Study of Key Correlates for Household Transmission of SARS-CoV-2 | Efficacy and safety of antimicrobial stewardship prospective audit and feedback in patients hospitalized with COVID-19 (COVASP): a pragmatic, cluster-randomized, non-inferiority trial | COVID-19 and Risk for Mental Disorders Among Adults in Denmark

May 24, 2023

FDA voted in favor of approving the Abrysvo vaccine | Safety of the BNT162b2 COVID-19 Vaccine in Children Aged 5 to 17 Years | Statement on the antigen composition of COVID-19 vaccines | Canine Olfactory Detection of SARS-CoV-2-Infected Humans | CDC HIV surveillance report

May 18, 2023

Risk of post-acute sequelae of SARS-CoV-2 infection associated with pre-coronavirus disease obstructive sleep apnea diagnoses: an electronic health record-based analysis from the RECOVER initiative | Trajectories of the evolution of post COVID-19 condition, up to two years after symptoms onset | Virus variant specific clinical performance of a SARS-CoV-2 rapid antigen test with focus on omicron VOC. | COVID-19 mortality among selective serotonin reuptake inhibitor users - Results from a nationwide cohort | Efficacy of cognitive behavioral therapy targeting severe fatigue following COVID-19: results of a randomized controlled trial

May 11, 2023

Impact of SARS-CoV-2 Variants on Inpatient Clinical Outcome | Immunogenicity and tolerability of a bivalent virus-like particle norovirus vaccine candidate in children from 6 months up to 4 years of age: A phase 2 randomized, double-blind trial | An influenza hemagglutinin stem nanoparticle vaccine induces cross-group 1 neutralizing antibodies in healthy adults | Targeted Vaccine Messaging to Promote COVID-19 Vaccines for Children and Youth | Vaccines and Related Biological Products Advisory Committee Meeting June 15, 2023 Announcement | Gut microbiota‐derived synbiotic formula (SIM01) as a novel adjuvant therapy for COVID‐19: An open‐label pilot study | COVID-19 Surveillance After Expiration of the Public Health Emergency Declaration | Provisional Mortality Data | Prevalence of Post-Coronavirus Disease Condition 12 Weeks After Omicron Infection Compared With Negative Controls and Association With Vaccination Status

May 04, 2023

Long COVID brain fog and muscle pain are associated with longer time to clearance of SARS-CoV-2 RNA | U.S. Food and Drug Administration approved Arexvy, the first respiratory syncytial virus (RSV) vaccine approved for use in the United States | Vaccination with BCG-Denmark did not result in a lower risk of Covid-19 among health care workers than placebo |NVX-CoV2373 vaccine efficacy against hospitalization: A post hoc analysis of the PREVENT-19 phase 3, randomized, placebo-controlled trial | Comparative effectiveness of the sars-CoV-2 vaccines during Delta dominance | Clinical Outcomes Following Treatment for COVID-19 | Real-life experience with remdesivir for treatment of COVID-19 among older adults: a multicentre retrospective study | Association between SARS-CoV-2 and metagenomic content of samples from the Huanan Seafood Market | Researchers disagree over how bad it is to be reinfected, and whether COVID-19 can cause lasting changes to the immune system | Virtual Care and Emergency Department Use During the COVID-19 Pandemic Among Patients of Family Physicians in Ontario, Canada | Assessment of Gender-Specific COVID-19 Case Fatality Risk per Malignant Neoplasm Type | Timing of intubation and ICU mortality in COVID-19 patients

Situation Dashboards

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World Health Organization (WHO)

Novel Coronavirus (COVID-19) Situation from World Health Organization (WHO)
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Johns Hopkins University (JHU)

Coronavirus COVID-19 Global Cases by the Center for Systems Science and Engineering (CSSE) at JHU
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COVID-19 in US and Canada

1Point3Acres Real-Time Coronavirus (COVID-19) Updates in US and Canada with Credible Sources
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Genomic Epidemiology COVID-19

Genomic Epidemiology of (COVID-19) Maintained by the Nextstrain team, enabled by data from GISAID.

Sources for COVID-19 Information

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World Health Organization (WHO)

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Centers for Disease Control, US

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International Society for Infectious Diseases

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This Week in Virology (TWIV)

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