Weekly Clinical Updates

• WHO estimate: 115,000 health workers have died from Covid-19, as calls for vaccine access grow • Virologic features of SARS-CoV-2 infection in children • COVID-19 Vaccination and Non–COVID-19 Mortality Risk • Association of Statins and 28-Day Mortality in Patients Hospitalized with SARS CoV-2 Infection • Assessment of Cognitive Function in Patients After COVID-19 Infection • Covid-19 Breakthrough Infections in Vaccinated Health Care Workers • Coronavirus (COVID-19) Update: FDA Takes Additional Actions on the Use of a Booster Dose for COVID-19 Vaccines • FACT SHEET FOR HEALTH CARE PROVIDERS: EMERGENCY USE AUTHORIZATION (EUA) OF REGEN-COV • Effect of early treatment with fluvoxamine on risk of emergency care and hospitalisation among patients with COVID-19: the TOGETHER randomised, platform clinical trial • Routine Vaccination Coverage — Worldwide, 2020 Antibody Testing Is Not Currently Recommended to Assess Immunity After COVID-19 Vaccination: FDA Safety Communication • The Flawed Science of Antibody Testing for SARS-CoV-2 Immunity

Effect of Antithrombotic Therapy on Clinical Outcomes in Outpatients With Clinically Stable Symptomatic COVID-19 | Comprehensive antibody profiling of mRNA vaccination in children | Heterologous SARS-CoV-2 Booster Vaccinations – Preliminary Report | WHO, UN set out steps to meet world COVID vaccination targets

The durability of immunity against reinfection by SARS-CoV-2: a comparative evolutionary study | IVIG Compared to IVIG Plus Infliximab in Multisystem Inflammatory Syndrome in Children | AZD7442 request for Emergency Use Authorization for COVID-19 prophylaxis filed in US | COVID-19 Outbreaks at Youth Summer Camps — Louisiana, June–July 2021

Incidence, co-occurrence, and evolution of long-COVID features: A 6-month retrospective cohort study of 273,618 survivors of COVID-19 | Safety Monitoring of an Additional Dose of COVID-19 Vaccine — United States, August 12–September 19, 2021 | Impact of Timing of Tocilizumab Use in Hospitalized Patients With SARS-CoV-2 Infection

Virologic features of SARS-CoV-2 infection in children | Steroids use in non-oxygen requiring COVID-19 patients: a systematic review and meta-analysis | NIH builds large nationwide study population of tens of thousands to support research on long-term effects of COVID-19 The COVID-19 Hospitalization Metric in the Pre- and Post-vaccination Eras as a Measure of Pandemic Severity: A Retrospective, Nationwide Cohort Study | High genetic barrier to escape from human polyclonal SARS-CoV-2 neutralizing antibodies | Considerations in boosting COVID-19 vaccine immune responses | HHS Announces State/territory-coordinated Distribution System for Monoclonal Antibody Therapeutics | Daily testing for contacts of individuals with SARS-CoV-2 infection and attendance and SARS-CoV-2 transmission in English secondary schools and colleges: an open-label, cluster-randomised trial | SARS-CoV-2 Transmission to Masked and Unmasked Close Contacts of University Students with COVID-19 — St. Louis, Missouri, January–May 2021 | A year of genomic surveillance reveals how the SARS-CoV-2 pandemic unfolded in Africa

Long-Term Symptoms Among Adults Tested for SARS-CoV-2 — United States, January 2020–April 2021 | Overlooked Shortcomings of Observational Studies of Interventions in Coronavirus Disease 2019: An Illustrated Review for the Clinician | Long-Term Symptoms Among Adults Tested for SARS-CoV-2