Weekly Clinical Updates

As infectious diseases such as SARS, Monkeypox, Polio, HIV, and Ebola travel the globe and garner media attention, Parasites Without Borders staff are curating resources in a timely, ongoing basis. We believe the information posted here is worthy of further examination by the science and medical communities. Our primary goal remains to bring the latest medical and biological information to the forefront for researchers and practicing physicians.

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July 20, 2023

Omicron subvariant BA.5 efficiently infects lung cells | The immunology of long COVID | FDA Approved a New Drug to Prevent RSV in Babies and Toddlers | COVID-19 scent dog research highlights and synthesis during the pandemic of December 2019-April 2023 | Transmission of SARS-CoV-2 in free-ranging white-tailed deer in the United States

July 13, 2023

Exaggerated blood pressure elevation in response to orthostatic challenge, a post-acute sequelae of SARS-CoV-2 infection (PASC) after hospitalization | Long term follow-up of a multicentre cohort of COVID-19 patients with pulmonary embolism: Anticoagulation management and outcomes | Development of monoclonal antibody-based blocking ELISA for detecting SARS-CoV-2 exposure in animals | Repeated antibiotic exposure and risk of hospitalization and death following COVID-19 infection | The Coronavirus Disease 2019 Rebound Study: A Prospective Cohort Study to Evaluate Viral and Symptom Rebound Differences in Participants Treated With Nirmatrelvir Plus Ritonavir Versus Untreated Controls | Risk of Cardiovascular Disease After COVID‐19 Diagnosis Among Adults With and Without Diabetes

July 05,2023

Autochthonous Leprosy in the United States | A systematic review to identify novel clinical characteristics of monkeypox virus infection and therapeutic and preventive strategies to combat the virus | Genome-wide Association Study of Long COVID | Two-year duration of immunity of inactivated poliovirus vaccine: A follow-up study in Pakistan in 2020 | Evaluation of novel oral polio vaccine type 2 SIA impact in a large outbreak of circulating vaccine-derived poliovirus in Nigeria | Effectiveness of the Coronavirus Disease 2019 Bivalent Vaccine | Oral Nirmatrelvir and Ritonavir for Covid-19 in Vaccinated, Non-Hospitalized Adults, Ages 18-50 Year | Vaccination Ameliorates Cellular Inflammatory Responses in SARS-CoV-2 Breakthrough Infections |Performance of Rapid Antigen Tests to Detect Symptomatic and Asymptomatic SARS-CoV-2 Infection | High incidence of autonomic dysfunction and postural orthostatic tachycardia syndrome in patients with long-COVID: Implications for management and healthcare planning

June 29, 2023

Intrinsic and effective severity of COVID-19 cases infected with the ancestral strain and Omicron BA.2 variant in Hong Kong | Female reproductive health impacts of Long COVID and associated illnesses including ME/CFS, POTS, and connective tissue disorders: a literature review | Awake prone positioning for non-intubated patients with COVID-19-related acute hypoxic respiratory failure: a systematic review based on eight high-quality randomized controlled trials | Guidance on Measles during the Summer Travel Season

June 22,2023

Updated COVID-19 Vaccines for Use in the United States Beginning in Fall 2023 | Prevention of COVID-19 Following a Single Intramuscular Administration of Adintrevimab: Results From a Phase 2/3 Randomized, Double-Blind, Placebo-Controlled Trial (EVADE) | Real-World Effectiveness of Nirmatrelvir/Ritonavir on Coronavirus Disease 2019 (COVID-19)–Associated Hospitalization Prevention: A Population-based Cohort Study in the Province of Quebec, Canada. | Coronavirus Disease 2019 Convalescent Plasma Outpatient Therapy to Prevent Outpatient Hospitalization: A Meta-Analysis of Individual Participant Data From 5 Randomized Trials | Association of Culturable-Virus Detection and Household Transmission of SARS-CoV-2, California and Tennessee, 2020–2022

June 15, 2023

Anemia as a risk factor for disease progression in patients admitted for COVID-19 | Impact of fatigue as the primary determinant of functional limitations among patients with post-COVID-19 syndrome | Post-COVID condition in patients with inflammatory rheumatic diseases | Persistent serum protein signatures define an inflammatory subcategory of long COVID | The relevance of pacing strategies in managing symptoms of post-COVID-19 syndrome | Genetic stabilization of attenuated oral vaccines against poliovirus types 1 and 3 | Evaluation of Oseltamivir Used to Prevent Hospitalization in Outpatients With Influenza | Has COVID-19 Threatened Routine Childhood Vaccination? Insights From US Public Opinion Polls | Successful Treatment of Persistent Symptomatic Coronavirus Disease 19 (COVID-19) Infection with Extended Duration Nirmatrelvir/Ritonavir| Outpatient treatment of COVID-19 and incidence of post-COVID-19 condition over 10 months (COVID-OUT) | Metformin reduces SARS-CoV-2 in a Phase 3 Randomized Placebo Controlled Clinical Trial | To Track Progress Toward Poliomyelitis Eradication — Worldwide, 2021–2022 | Viral emissions into the air and environment after SARS-CoV-2 human challenge: a phase 1, open label, first-in-human study

Situation Dashboards

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World Health Organization (WHO)

Novel Coronavirus (COVID-19) Situation from World Health Organization (WHO)
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Johns Hopkins University (JHU)

Coronavirus COVID-19 Global Cases by the Center for Systems Science and Engineering (CSSE) at JHU
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COVID-19 in US and Canada

1Point3Acres Real-Time Coronavirus (COVID-19) Updates in US and Canada with Credible Sources
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Genomic Epidemiology COVID-19

Genomic Epidemiology of (COVID-19) Maintained by the Nextstrain team, enabled by data from GISAID.

Sources for COVID-19 Information

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World Health Organization (WHO)

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Centers for Disease Control, US

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International Society for Infectious Diseases

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This Week in Virology (TWIV)

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