Weekly Clinical Updates

Human Neural Larva Migrans Caused by Ophidascaris robertsi Ascarid | The public health significance of finding autochthonous melioidosis cases | Clinical Outcomes Associated With Overestimation of Oxygen Saturation by Pulse Oximetry in Patients Hospitalized With COVID-19 | Project NextGen Awards Over $1.4 Billion to Develop the Future of COVID-19 Vaccines and Therapeutics | Differences in SARS-CoV-2 specific humoral and cellular immune responses | Pfizer and BioNTech Receive Positive CHMP (Committee for Medicinal Products for Human Use) Opinion for Omicron XBB.1.5-adapted COVID-19 Vaccine in the European Union | Clinical Antiviral Efficacy of Remdesivir in Coronavirus Disease 2019: An Open-Label, Randomized Controlled Adaptive Platform Trial (PLATCOV) | Optimal Duration of Systemic Corticosteroids in Coronavirus Disease 2019 Treatment | Excess All-Cause Mortality in China After Ending the Zero COVID Policy | International Pediatric COVID-19 Severity Over the Course of the Pandemic | Risk of autoimmune diseases following COVID-19 and the potential protective effect from vaccination

FDA Approves First Vaccine for Pregnant Individuals to Prevent RSV in Infants | Prevention and Control of Seasonal Influenza with Vaccines: Recommendations of the Advisory Committee on Immunization Practices — United States, 2023–24 Influenza Season | Nirmatrelvir resistance – de novo E166V/L50V mutations in an immunocompromised patient treated with prolonged nirmatrelvir/ritonavir monotherapy leading to clinical and virological treatment failure – a case report | Progress Toward Poliomyelitis Eradication — Pakistan, January 2022–June 2023 | Modeling poliovirus transmission and responses in New York State | Incidence of New-Onset Hypertension Post–COVID-19: Comparison With Influenza | Postacute sequelae of COVID-19 at 2 years

Safety Profile and Clinical and Virological Outcomes of Nirmatrelvir-Ritonavir Treatment in Patients With Advanced Chronic Kidney Disease and Coronavirus Disease 2019 (COVID-19) | The STOP COVID 2 study: Fluvoxamine vs placebo for outpatients with symptomatic COVID-19, a fully-remote randomized controlled trial | The effect of corticosteroids, antibiotics, and anticoagulants on the development of post-COVID-19 syndrome in COVID-19 hospitalized patients 6 months after discharge: a retrospective follow up study

Dynamics of inflammatory responses after SARS-CoV-2 infection by vaccination status in the USA: a prospective cohort study | Core mitochondrial genes are down-regulated during SARS-CoV-2 infection of rodent and human hosts | Immunogenicity, safety, and preliminary efficacy evaluation of OVX836, a nucleoprotein-based universal influenza A vaccine candidate: a randomised, double-blind, placebo-controlled, phase 2a trial

NIH has launched several phase 2 long-COVID treatment trials | Effectiveness of Oral Nirmatrelvir/Ritonavir vs. Intravenous Three-Day Remdesivir in Preventing Progression to Severe COVID-19: A Single-Center, Prospective, Comparative, Real-Life Study | Rapid Direct Detection of SARS-CoV-2 Aerosols in Exhaled Breath at the Point of Care | Predicting COVID-19 Incidence Using Wastewater Surveillance Data, Denmark, October 2021–June 2022 | Use of Wastewater Metrics to Track COVID-19 in the US published in JAMA Network Open | Wastewater-based epidemiology predicts COVID-19-induced weekly new hospital admissions in over 150 USA countie | Association between duration of SARS-CoV-2 positivity and long COVID

Case Report of Leprosy in Central Florida, USA, 2022 | A common allele of HLA is associated with asymptomatic SARS-CoV-2 infection | Delayed intubation associated with in-hospital mortality in patients with COVID-19 respiratory failure who fail heated and humified high flow nasal canula | Blood Group A Enhances SARS-CoV-2 Infection | Clinical phenotypes and quality of life to define post-COVID-19 syndrome: a cluster analysis of the multinational, prospective ORCHESTRA cohort | Use of Respiratory Syncytial Virus Vaccines in Older Adults: Recommendations of the Advisory Committee on Immunization Practices — United States, 2023