Weekly Clinical Updates

As infectious diseases such as SARS, Monkeypox, Polio, HIV, and Ebola travel the globe and garner media attention, Parasites Without Borders staff are curating resources in a timely, ongoing basis. We believe the information posted here is worthy of further examination by the science and medical communities. Our primary goal remains to bring the latest medical and biological information to the forefront for researchers and practicing physicians.

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An Examination of School Reopening Strategies during the SARS-CoV-2 Pandemic

April 16, 2022

Children and COVID-19: State Date Report | Symptom prevalence, duration, and risk of hospital admission in individuals infected with SARS-CoV-2 during periods of omicron and delta variant dominance | Infectious viral load in unvaccinated and vaccinated individuals infected with ancestral, Delta or Omicron SARS-CoV-2 | Myopericarditis following COVID-19 vaccination and non-COVID-19 vaccination | Fluvoxamine for Outpatient Management of COVID-19 to Prevent Hospitalization | Veru’s Novel COVID-19 Drug Candidate Reduces Deaths in Hospitalized Patients in Interim Analysis... | Comparison of Rapid Antigen Tests′ | SARS-CoV-2 infection in Africa: A systematic review and meta-analysis of standardised seroprevalence studies
people wearing face protection from infection of corona virus

April 9, 2022

Cardiac Complications After SARS-CoV-2 Infection and mRNA COVID-19 Vaccination — PCORnet, United States, January 2021–January 2022 | Clinical characteristics, activity levels and mental health problems in children with long coronavirus disease: a survey of 510 children | Short-term Outcomes of Corticosteroid Monotherapy in Multisystem Inflammatory Syndrome in Children | Protection by a Fourth Dose of BNT162b2 against Omicron in Israel | Long-term outcomes of dexamethasone 12 mg versus 6 mg in patients with COVID-19 and severe hypoxaemia
Ill blond senior woman sitting at home, taking oxygen from respirator while nurse sitting next to her and holding her hand.

April 2, 2022

Effect of Early Treatment with Ivermectin among Patients with COVID-19 | Effect of Antiplatelet Therapy on Survival and Organ Support–Free Days in Critically Ill Patients With COVID-19A Randomized Clinical Trial | Association of Early Aspirin Use With In-Hospital Mortality in Patients With Moderate COVID-19 | Prone positioning of patients with moderate hypoxaemia due to covid-19: multicenter pragmatic randomized trial (COVID-PRONE) | U.S. Food and Drug Administration authorized a second booster dose of either the Pfizer-BioNTech or the Moderna COVID-19 vaccines for older people and certain immunocompromised individuals
Schoolkids disinfecting hands during coronavirus pandemic.

March 26, 2022

COVID-19–Associated Hospitalizations Among Adults During SARS-CoV-2 Delta and Omicron Variant Predominance, by Race/Ethnicity and Vaccination Status — COVID-NET, 14 States, July 2021–January 2022 | Intrinsic Severity of SARS-CoV-2 Omicron BA.2 in Uninfected, Unvaccinated Children: A Population-Based, Case-Control Study on Hospital Complications | SARS-CoV-2 Placentitis and Intraparenchymal Thrombohematomas Among COVID-19 Infections in Pregnancy | De novo emergence of a remdesivir resistance mutation during treatment of persistent SARS-CoV-2 infection in an immunocompromised patient: a case report
Four diverse male and female senior friends wearing face masks showing plasters after vaccination

March 19, 2022

Children and COVID19: State Level Data Report | Hospitalization of Infants and Children Aged 0–4 Years with Laboratory-Confirmed COVID-19 — COVID-NET, 14 States, March 2020–February 2022 | Effectiveness of 2-Dose BNT162b2 (Pfizer BioNTech) mRNA Vaccine in Preventing SARS-CoV-2 Infection Among Children Aged 5–11 Years and Adolescents Aged 12–15 Years — PROTECT Cohort, July 2021–February 2022 | High vaccine effectiveness against severe Covid-19 in the elderly in Finland before and after the emergence of Omicron | Comparison of Seroconversion in Children and Adults With Mild COVID-19
Two Medical Scientists in the Brain Research Laboratory

March 12, 2022

SARS-CoV-2 is associated with changes in brain structure | New Onset Dementia Among Survivors of Pneumonia Associated with Severe Acute Respiratory Syndrome Coronavirus 2 Infection | Whole genome sequencing reveals host factors underlying critical Covid-19 | Association Between Dexamethasone Treatment After Hospital Discharge for Patients With COVID-19 Infection and Rates of Hospital Readmission and Mortality | Pfizer Initiated a Phase 2/3 Study of their Novel COVID-19 Oral Treatment in Pediatric Participants | Efficacy of Antiviral Agents against the SARS-CoV-2 Omicron Subvariant BA.2

Situation Dashboards

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World Health Organization (WHO)

Novel Coronavirus (COVID-19) Situation from World Health Organization (WHO)
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Johns Hopkins University (JHU)

Coronavirus COVID-19 Global Cases by the Center for Systems Science and Engineering (CSSE) at JHU
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COVID-19 in US and Canada

1Point3Acres Real-Time Coronavirus (COVID-19) Updates in US and Canada with Credible Sources
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Genomic Epidemiology COVID-19

Genomic Epidemiology of (COVID-19) Maintained by the Nextstrain team, enabled by data from GISAID.

Sources for COVID-19 Information

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World Health Organization (WHO)

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Centers for Disease Control, US

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International Society for Infectious Diseases

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This Week in Virology (TWIV)

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