Weekly Clinical Updates

As infectious diseases such as SARS, Monkeypox, Polio, HIV, and Ebola travel the globe and garner media attention, Parasites Without Borders staff are curating resources in a timely, ongoing basis. We believe the information posted here is worthy of further examination by the science and medical communities. Our primary goal remains to bring the latest medical and biological information to the forefront for researchers and practicing physicians.

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April 19, 2023

Update on Vaccine-Derived Poliovirus Outbreaks | Sleep Disturbance Severity and Correlates | Two individuals with potential monkeypox virus reinfection | Risk of autoimmune diseases in patients | FDA Authorizes Changes to Simplify Use of Bivalent mRNA COVID-19 Vaccines | SARS-CoV-2 neutralizing antibodies | Durability of Bivalent Boosters against Omicron Subvariants | Nirmatrelvir and risk of hospital admission or death in adults | Evolving Real-World Effectiveness of Monoclonal Antibodies | Effect of Angiotensin-Converting Enzyme Inhibitor | Efficacy and Safety of Anakinra Plus Standard | Higher dose corticosteroids in patients admitted to hospital | Risk of Death in Patients Hospitalized for COVID-19 | Recent French mpox cluster includes fully vaccinated patients | Epidemiologic and Clinical Features of Mpox-Associated Deaths | SARS-CoV-2 During Omicron Variant Predominance | Severe Maternal Morbidity and Mortality of Pregnant Patients | Sickness presenteeism in healthcare workers | Ventilation Improvements Among K–12 Public School Districts | Risk factors and vectors for SARS-CoV-2 household transmission | Definition of Post–COVID-19 Condition

April 05, 2023

Prevalence and Characteristics Associated With Post–COVID-19 Condition | The Breadth of the Neutralizing Antibody Response to Original SARS-CoV-2 Infection | Pathogenesis Underlying Neurological Manifestations of Long COVID Syndrome | Vaccine effectiveness against hospitalization among adolescent cases | Effectiveness of BNT162b2 after extending the primary series dosing interval in children | Within-host genetic diversity of SARS-CoV-2 | Live-attenuated vaccine sCPD9 elicits superior mucosal and systemic immunity to SARS-CoV-2 variants | Fc-γR-dependent antibody effector functions are required for vaccine-mediated protection | COVID-19 convalescent plasma utilization in the United States | FDA authorizes Gohibic (vilobelimab) injection for the treatment of COVID-19 | Anti-C5a antibody IFX-1 (vilobelimab) treatment versus best supportive care for patients | Anti-C5a antibody (vilobelimab) therapy for critically ill patients | Triple combination therapy with two antivirals | Adeno-associated virus type 2 in US children | Genomic investigations of unexplained acute hepatitis in children | Surveillance of SARS-CoV-2 at the Huanan Seafood Market

March 30, 2023

Severe Infection and Risk of Cardiovascular Disease | Risk Factors Associated With Post−COVID-19 Condition | Maternal third dose of BNT162b2 mRNA vaccine and risk of infant COVID-19 hospitalization | Association of Treatment With Nirmatrelvir and the Risk of Post–COVID-19 Condition | Antibiotics don't reduce risk of death from viral respiratory infections | ABO blood types and SARS-CoV-2 infection assessed using seroprevalence data in a large population-based sample: the SAPRIS-SERO multi-cohort study | Mechanically Ventilated Patients With Coronavirus Disease 2019 Had a Higher Chance of In-Hospital Death If Treated With High-Flow Nasal Cannula Oxygen Before Intubation

March 23, 2023

Prior COVID-19 infection associated with increased risk of newly diagnosed erectile dysfunction | A novel tool to eradicate an ancient scourge: the novel oral polio vaccine type 2 story | Correlates of protection against COVID-19 infection and intensity of symptomatic disease in vaccinated individuals exposed to SARS-CoV-2 in households | Effectiveness of nirmatrelvir–ritonavir in preventing hospital admissions and deaths in people with COVID-19: a cohort study in a large US health-care system | Projected COVID-19 Mortality Reduction From Paxlovid Rollout | SARS-CoV-2 mRNA vaccines decouple anti-viral immunity from humoral autoimmunity | Adverse maternal, fetal, and newborn outcomes among pregnant women with SARS-CoV-2 infection: an individual participant data meta-analysis | Correlates of protection and viral load trajectories in omicron breakthrough infections in triple vaccinated healthcare workers

March 16, 2023

Clinical Characteristics and Outcomes of Children With SARS-CoV-2 Infection During the Delta and Omicron Variant-Dominant Periods in Korea | Assessment of the Risk of Venous Thromboembolism in Nonhospitalized Patients With COVID-19 | Clearance of longstanding, immune-deficiency-associated, vaccine-derived polio virus infection following remdesivir therapy for chronic SARS-CoV-2 infection | Outpatient Treatment of COVID-19 and the Development of Long COVID Over 10 Months | Nirmatrelvir and the Risk of Post-Acute Sequelae of COVID-19 | Optimal Duration of Systemic Corticosteroids in COVID-19 Treatment | SARS-CoV-2 Exposure in Norway Rats (Rattus norvegicus) from New York City | Exhaled Breath Aerosol Shedding of Highly Transmissible Versus Prior Severe Acute Respiratory Syndrome Coronavirus 2 Variants

March 09, 2023

Community-onset bacterial coinfection in children critically ill with SARS-CoV-2 infection | Risk of Coronavirus Disease 2019–Associated Pulmonary Aspergillosis Based on Corticosteroid Duration | Cardiac abnormalities in Long COVID 1-year post-SARS-CoV-2 infection | Long-term gastrointestinal outcomes of COVID-19 | Confronting the evolution and expansion of anti-vaccine activism in the USA | Effectiveness of Maternal Influenza Vaccination in Peru PRIME Cohort | Bivalent booster effectiveness against severe COVID-19 outcomes in Finland | Immunomodulators for severe coronavirus disease-2019 in transplant patients | Characteristics and predictors of persistent symptoms post-COVID-19 in children and young people | Parental Nonadherence to Health Policy Recommendations for Prevention of COVID-19 | Viral kinetics of sequential SARS-CoV-2 infections | Long-term cardiovascular outcomes in COVID-19 survivors among non-vaccinated population | One-Year Adverse Outcomes Among US Adults With Post–COVID-19 Condition

Situation Dashboards

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World Health Organization (WHO)

Novel Coronavirus (COVID-19) Situation from World Health Organization (WHO)
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Johns Hopkins University (JHU)

Coronavirus COVID-19 Global Cases by the Center for Systems Science and Engineering (CSSE) at JHU
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COVID-19 in US and Canada

1Point3Acres Real-Time Coronavirus (COVID-19) Updates in US and Canada with Credible Sources
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Genomic Epidemiology COVID-19

Genomic Epidemiology of (COVID-19) Maintained by the Nextstrain team, enabled by data from GISAID.

Sources for COVID-19 Information

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World Health Organization (WHO)

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Centers for Disease Control, US

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International Society for Infectious Diseases

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This Week in Virology (TWIV)

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