Weekly Clinical Updates

As infectious diseases such as SARS, Monkeypox, Polio, HIV, and Ebola travel the globe and garner media attention, Parasites Without Borders staff are curating resources in a timely, ongoing basis. We believe the information posted here is worthy of further examination by the science and medical communities. Our primary goal remains to bring the latest medical and biological information to the forefront for researchers and practicing physicians.

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September 15, 2021

Long-Term Symptoms Among Adults Tested for SARS-CoV-2 — United States, January 2020–April 2021 | Overlooked Shortcomings of Observational Studies of Interventions in Coronavirus Disease 2019: An Illustrated Review for the Clinician | Long-Term Symptoms Among Adults Tested for SARS-CoV-2

September 10, 2021

Ivermectin Intended for Animals: Letter to Stakeholders - Do Not Use in Humans as a Treatment for COVID-19 | Characteristics and Outcomes of Women With COVID-19 Giving Birth at US Academic Centers During the COVID-19 Pandemic | Children and COVID-19: State-Level Data Report | Long COVID - the physical and mental health of children and non-hospitalised young people 3 months after SARS-CoV-2 infection; a national matched cohort study (The CLoCk) Study. | Outbreak Associated with SARS-CoV-2 B.1.617.2 (Delta) Variant in an Elementary School — Marin County, California, May–June 2021 | 1-year outcomes in hospital survivors with COVID-19: a longitudinal cohort study | Convalescent plasma recommendations from IDSA

September 3, 2021

Unvaccinated COVID-19 hospitalizations cost the U.S. health system billions of dollars | Comirnaty and PfizeSARS-CoV-2 Infections and Hospitalizations Among Persons Aged ≥16 Years | A third COVID-19 vaccine shot markedly boosts neutralizing antibody potency and breadth | Durability of antibody responses elicited by a single dose of Ad26.COV2.S and substantial increase following late boosting |.Virological characteristics of SARS-CoV-2 vaccine breakthrough infections in health care workers | COVID-19 Transmission Dynamics Among Close Contacts of Index Patients With COVID-19 | COVID-19 false dichotomies and a comprehensive review of the evidence regarding public health, COVID-19 symptomatology, SARS-CoV-2 transmission, mask wearing, and reinfection

August 23, 2021

The SARS-CoV-2 Delta variant and its sublineages (B.1.617.2, AY.1, AY.2, AY.3; [1]) can cause high viral loads, are highly transmissible, and contain mutations that confer partial immune escape [2,3]. Using PCR threshold cycle (Ct) data from a single large contract laboratory, authors show that individuals in Wisconsin, USA had similar viral RNA loads in nasal swabs, irrespective of vaccine status, during a time of high and increasing prevalence of the Delta variant. Infectious SARS-CoV-2 was isolated from 51 of 55 specimens (93%) with Ct <25 from both vaccinated and unvaccinated persons, indicating that most individuals with Ct values in this range (Wilson 95% CI 83%-97%) shed infectious virus regardless of vaccine status. Notably, 68% of individuals infected despite vaccination tested positive with Ct <25, including at least 8 who were asymptomatic at the time of testing.

August 18, 2021

An Examination of School Reopening Strategies during the SARS-CoV-2 Pandemic | Effect of Convalescent Plasma on Mortality among Hospitalized Patients with COVID-19: Initial Three-Month Experience | Seroprevalence of anti-SARS-CoV-2 IgG antibodies in Kenyan blood donors

August 10, 2021

An Examination of School Reopening Strategies during the SARS-CoV-2 Pandemic | Effect of Convalescent Plasma on Mortality among Hospitalized Patients with COVID-19: Initial Three-Month Experience | Seroprevalence of anti-SARS-CoV-2 IgG antibodies in Kenyan blood donors

Situation Dashboards

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World Health Organization (WHO)

Novel Coronavirus (COVID-19) Situation from World Health Organization (WHO)
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Coronavirus COVID-19 Global Cases by the Center for Systems Science and Engineering (CSSE) at JHU
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COVID-19 in US and Canada

1Point3Acres Real-Time Coronavirus (COVID-19) Updates in US and Canada with Credible Sources
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Genomic Epidemiology COVID-19

Genomic Epidemiology of (COVID-19) Maintained by the Nextstrain team, enabled by data from GISAID.

Sources for COVID-19 Information

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World Health Organization (WHO)

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Centers for Disease Control, US

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International Society for Infectious Diseases

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This Week in Virology (TWIV)

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